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(Generic name: Quetiapine)
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WARNING: Take
Seroquel - Quetiapine And All Prescriptions Medications Only As Directed By Your
Doctor. If You have any questions about possible Seroquel side effects be sure
to ask your doctor or pharmacist!
IMPORTANT WARNING:
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Use in Older Adults:
Studies have shown that older adults with dementia
(a brain disorder that affects the ability to remember, think clearly,
communicate, and perform daily activities and that may cause changes in
mood and personality) who take antipsychotics (medications for mental
illness) such as quetiapine have an increased risk of death during
treatment. If you experience any of the following symptoms, call your
doctor immediately: slow or difficult speech, sudden dizziness or
faintness, or weakness or numbness of an arm or leg.
Quetiapine is not approved by the Food and Drug
Administration (FDA) for the treatment of behavioral problems in older
adults with dementia. Talk to the doctor who prescribed this medication
if you, a family member, or someone you care for has dementia and is
taking quetiapine. For more information visit the FDA website:
http://www.fda.gov/cder
Use in Children and Teenagers:
Studies have shown that children and teenagers who
take antidepressants ('mood elevators') such as quetiapine may be more
likely to think about harming or killing themselves or to plan or try to
do so than children who do not take antidepressants. Children should not
normally take quetiapine.
If your child's doctor has prescribed quetiapine for
your child, you should watch his or her behavior and mood very
carefully, especially at the beginning of treatment and any time his or
her dose is increased or decreased. Your child may develop serious
symptoms very suddenly, so it is important to pay attention to his or
her behavior or mood every day. Call your child's doctor right away if
he or she experiences any of these symptoms: new or worsening
depression; thinking about harming or killing him/herself or planning or
trying to do so; extreme worry; agitation; panic attacks; difficulty
falling asleep or staying asleep; irritability; aggressive behavior;
acting without thinking; severe restlessness; frenzied abnormal
excitement; or any other sudden or unusual changes in behavior or mood.
Your child's doctor will want to see your child
often while he or she is taking quetiapine, especially at the beginning
of his or her treatment. Your child's doctor may also want to speak with
you or your child by telephone from time to time. Be sure that your
child keeps all appointments for office visits or telephone
conversations with his or her doctor.
Your child's doctor or pharmacist will give you the
manufacturer's patient information sheet (Medication Guide) when your
child begins treatment with quetiapine. Read the information carefully
and ask your child's doctor or pharmacist if you have any questions. You
can also obtain the Medication Guide from the FDA website:
http://www.fda.gov/cder/drug/antidepressants/MG_template.pdf.
Talk to your child's doctor about the risks of
giving quetiapine to your child. |
Why is this medication prescribed?
Quetiapine is used to treat the symptoms of schizophrenia (a
mental illness that causes disturbed or unusual thinking, loss of interest in
life, and strong or inappropriate emotions). It is also used to treat episodes
of mania (frenzied, abnormally excited or irritated mood) or depression in
patients with bipolar disorder (manic depressive disorder; a disease that causes
episodes of depression, episodes of mania, and other abnormal moods). Quetiapine
is in a class of medications called atypical antipsychotics. It works by
changing the activity of certain natural substances in the brain.
How should this medicine be used?
Quetiapine comes as a tablet to take by mouth. It is usually
taken one to three times a day. Take quetiapine at around the same time(s) every
day. Follow the directions on your prescription label carefully, and ask your
doctor or pharmacist to explain any part you do not understand. Take quetiapine
exactly as directed. Do not take more or less of it or take it more often than
prescribed by your doctor.
Your doctor will probably start you on a low dose of
quetiapine and gradually increase your dose during the first week of your
treatment. Ask your doctor or pharmacist if you have any questions about the
amount of medication you should take each day at the beginning of your treatment
Quetiapine may help control your symptoms but will not cure
your condition. Continue to take quetiapine even if you feel well. Do not stop
taking quetiapine without talking to your doctor. Your doctor will probably want
to decrease your dose gradually.
Other uses for this medicine
This medication may be prescribed for other uses; ask your
doctor or pharmacist for more information.
What special precautions should I follow?
Before taking quetiapine,
- tell your doctor and pharmacist if you are allergic to quetiapine or any
other medications.
- tell your doctor and pharmacist what prescription and nonprescription
medications, vitamins, nutritional supplements and herbal products you are
taking or plan to take. Be sure to mention any of the following:
antidepressants; certain antifungals such as fluconazole (Diflucan),
itraconazole (Sporanox), ketoconazole (Nizoral), and voriconazole (Vfend);
antihistamines; barbiturates; carbamazepine (Tegretol); divalproex (Depakote);dopamine
agonists such as bromocriptine (Parlodel), cabergoline (Dostinex), levodopa
(Dopar, Larodopa), pergolide (Permax), and ropinirole (Requip); erythromycin
(E.E.S., E-Mycin, Erythrocin); lorazepam (Ativan); medications for anxiety,
high blood pressure, irritable bowel disease, mental illness, motion
sickness, Parkinson's disease, ulcers, or urinary problems; phenobarbital
(Luminal); phenytoin (Dilantin); rifampin (Rifadin, Rimactane); sedatives;
oral steroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol),
and prednisone (Deltasone); sleeping pills; thioridazine (Mellaril); and
tranquilizers. Your doctor may need to change the doses of your medications
or monitor you carefully for side effects.
- tell your doctor if you or anyone in your family has or ever had
depression, bipolar disorder or mania, or if you or anyone in your family
has thought about or attempted suicide.Also tell your doctor if you or
anyone in your family has or has ever had diabetes. Also tell your doctor if
you have ever used street drugs or overused prescription medications and if
you have or have ever had any condition that makes it difficult for you to
swallow, seizures, high cholesterol, high or low blood pressure, a heart
attack, a stroke, breast cancer or thyroid, heart or liver disease. If you
have ever had to stop taking a medication for mental illness because of
severe side effects, be sure to tell your doctor.
- tell your doctor if you are pregnant or plan to become pregnant. If you
become pregnant while taking quetiapine, call your doctor. Do not breastfeed
while taking quetiapine.
- if you are having surgery, including dental surgery, tell your doctor or
dentist that you are taking quetiapine.
- you should know that quetiapine may make you drowsy. Do not drive a car
or operate machinery until you know how this medication affects you.
- you should know that alcohol can add to the drowsiness caused by this
medication. Do not drink alcohol while taking quetiapine.
- you should know that you may experience hyperglycemia (increases in your
blood sugar) while you are taking this medication, even if you do not
already have diabetes. If you have schizophrenia, you are more likely to
develop diabetes than people who do not have schizophrenia, and taking
quetiapine or similar medications may increase this risk. Tell your doctor
immediately if you have any of the following symptoms while you are taking
quetiapine: extreme thirst, frequent urination, extreme hunger, blurred
vision, or weakness. It is very important to call your doctor as soon as you
have any of these symptoms, because high blood sugar can cause a serious
condition called ketoacidosis. Ketoacidosis may become life-threatening if
it is not treated at an early stage. Symptoms of ketoacidosis include: dry
mouth, nausea and vomiting, shortness of breath, breath that smells fruity,
and decreased consciousness.
- you should know that your mental health may change in unexpected ways,
especially at the beginning of your treatment and any time that your dose is
increased or decreased. These changes may occur at any time if you have
depression or another mental illness, whether or not you are taking
quetiapine or any other medication. You, your family, or your caregiver
should call your doctor right away if you experience any of the following
symptoms: new or worsening depression; thinking about harming or killing
yourself or planning or trying to do so; extreme worry; agitation; panic
attacks; difficulty falling asleep or staying asleep; aggressive behavior;
irritability; acting without thinking; severe restlessness; and frenzied,
abnormal excitement. Be sure that your family knows which symptoms may be
serious so they can call the doctor if you are unable to seek treatment on
your own.
- you should know that quetiapine may make it harder for your body to cool
down when it gets very hot. Tell your doctor if you plan to do vigorous
exercise or be exposed to extreme heat.
- you should know that quetiapine may cause dizziness, lightheadedness,
and fainting when you get up too quickly from a lying position. This is more
common when you first start taking quetiapine and when your dose is
increased. To avoid this problem, get out of bed slowly, resting your feet
on the floor for a few minutes before standing up.
What special dietary instructions should I follow?
Talk to your doctor about eating grapefruit and drinking
grapefruit juice while taking this medicine.
Be sure to drink plenty of water every day while you are
taking this medication.
What should I do if I forget a dose?
Take the missed dose as soon as you remember it. However, if
it is almost time for the next dose, skip the missed dose and continue your
regular dosing schedule. Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Quetiapine may cause side effects. Tell your doctor if any
of these symptoms are severe or do not go away:
- drowsiness
- dizziness
- agitation
- pain
- weakness
- dry mouth
- indigestion
- constipation
- stomach pain
- headache
- excessive weight gain
- sore throat
Some side effects can be serious. If you experience any of
the following symptoms or those listed in the IMPORTANT WARNING or SPECIAL
PRECAUTIONS section, call your doctor immediately:
- fainting
- seizures
- changes in vision
- uncontrollable movements of your arms, legs, tongue, face, or lips
- painful erection of the penis that lasts for hours
- fever
- muscle stiffness, pain, or weakness
- excess sweating
- fast or irregular heartbeat
- confusion
- unusual bleeding or bruising
- hives
- rash
- blisters
- difficulty breathing or swallowing
Quetiapine may cause other side effects. Call your doctor if
you have any unusual problems while taking this medication.
Quetiapine has caused cataracts in laboratory animals. It is
not known if quetiapine may cause cataracts in humans. You will need to have eye
exams to check for cataracts at the beginning of your treatment and every six
months during your treatment. Talk to your doctor about the risks of taking
quetiapine.
If you experience a serious side effect, you or your doctor
may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse
Event Reporting program online [at
http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly
closed, and out of reach of children. Store it at room temperature and away from
excess heat and moisture (not in the bathroom). Throw away any medication that
is outdated or no longer needed. Talk to your pharmacist about the proper
disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center
at 1-800-222-1222. If the victim has collapsed or is not breathing, call local
emergency services at 911.
Symptoms of overdose may include:
- drowsiness
- dizziness
- fainting
- fast heartbeat
What other information should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your
pharmacist any questions you have about refilling your prescription.
Brand names
