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WARNING: Take
Ultram - Tramadol Hydrochloride And All Prescriptions Medications Only As
Directed By Your Doctor. If You have any questions about possible Ultram side
effects be sure to ask your doctor or pharmacist!
Why is this medication prescribed?
Tramadol is used to relieve moderate to moderately severe
pain. Tramadol extended-release tablets are only used by people who are expected
to need medication to relieve pain around-the-clock for a long time. Tramadol is
in a class of medications called opiate agonists. It works by changing the way
the body senses pain.
How should this medicine be used?
Tramadol comes as a tablet and an extended-release
(long-acting) tablet to take by mouth. The regular tablet is usually taken with
or without food every 4-6 hours as needed. The extended-release tablet should be
taken once a day. Take the extended-release tablet at about the same time of day
every day, and either always take it with food or always take it without food.
Take tramadol exactly as directed. Do not take more medication as a single dose
or take more doses per day than prescribed by your doctor. Taking more tramadol
than prescribed by your doctor may cause serious side effects or death.
Your doctor may start you on a low dose of tramadol and
gradually increase the amount of medication you take, not more often than every
3 days if you are taking the regular tablets or every 5 days if you are taking
the extended-release tablets.
Swallow the extended-release tablets whole; do not split,
chew, or crush them. Do not snort (inhale powder from crushed tablet) or inject
the dissolved extended-release tablets. Taking this medication in a way that is
not recommended may cause serious side effects or death.
Tramadol can be habit-forming. Do not take a larger dose,
take it more often, or take it for a longer period of time than prescribed by
your doctor. Call your doctor if you find that you want to take extra medication
or if you notice any other unusual changes in your behavior or mood.
Do not stop taking tramadol without talking to your doctor.
Your doctor will probably decrease your dose gradually.If you suddenly stop
taking tramadol you may experience withdrawal symptoms such as nervousness;
panic; sweating; difficulty falling asleep or staying asleep; runny nose,
sneezing, or cough; numbness, pain, burning, or tingling in your hands or feet;
hair standing on end; chills; nausea; uncontrollable shaking of a part of your
body; diarrhea; or rarely, hallucinations (seeing things or hearing voices that
do not exist).
Other uses for this medicine
This medication is sometimes prescribed for other uses; ask
your doctor or pharmacist for more information.
What special precautions should I follow?
Before taking tramadol,
tell your doctor and pharmacist if you are allergic to tramadol or other
opiate pain or cough medications such as meperidine (Demerol), morphine (Avinza,
Kadian, MS Contin), codeine (in some pain medications and cough syrups),
hydrocodone (in Vicodin), hydromorphone (Dilaudid), oxycodone (OxyContin, in
Percocet), propoxyphene (Darvon, Darvon N, in Darvocet), any other
medications, or any of the ingredients in tramadol tablets or
extended-release tablets. Ask your pharmacist for a list of ingredients in
tramadol tablets or extended release tablets.
- tell your doctor and pharmacist what other prescription and
nonprescription medications, vitamins, and nutritional supplements you are
taking. Be sure to mention any of the following: antifungal medications such
as ketoconazole (Nizoral); digoxin (Lanoxin); erythromycin (E.E.S., E-Mycin,
Erythrocin); monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan),
phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and
tranylcypromine (Parnate); medications for anxiety, mental illness, nausea,
and pain; medications for seizures, such as carbamazepine (Tegretol); muscle
relaxants such as cyclobenzaprine (Flexeril); promethazine (Phenergan);
quinidine; rifampin (Rifadin, Rifamate, Rimactane, others); sedatives;
sleeping pills; selective serotonin reuptake inhibitors (SSRIs) such as
citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox),
paroxetine (Paxil), and sertraline (Zoloft); tranquilizers; tricylic
antidepressants such as amitriptyline (Elavil), amoxapine (Asendin),
clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan),
imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil),
and trimipramine (Surmontil);and warfarin (Coumadin). Many other medications
may also interact with tramadol, so be sure to tell your doctor about all
the medications you are taking, even those that do not appear on this list.
Your doctor may need to change the doses of your medications or monitor you
carefully for side effects.
- tell your doctor what herbal products you are taking, especially St.
John's wort.
- tell your doctor if you have or have ever had seizures; an infection in
your brain or spine; a head injury, a brain tumor, a stroke, or any other
condition that caused high pressure inside your skull; depression or
thoughts about harming or killing yourself or planning or trying to do so;
diabetes; breathing problems or lung disease; or kidney or liver disease.
Also tell your doctor if you drink or have ever drunk large amounts of
alcohol, use or have ever used street drugs, or have overused prescription
medications.
- tell your doctor if you are pregnant, plan to become pregnant, or are
breast-feeding. If you become pregnant while taking tramadol, call your
doctor.
- if you are having surgery, including dental surgery, tell the doctor or
dentist that you are taking tramadol.
- you should know that this medication may make you drowsy and may affect
your coordination. Do not drive a car or operate machinery until you know
how this medication affects you.
- talk to your doctor about the safe use of alcohol while you are taking
this medication. Alcohol can make the side effects from tramadol worse.
- you should know that tramadol may cause dizziness, lightheadedness, and
fainting when you get up from a lying position. To avoid this, get out of
bed slowly, resting your feet on the floor for a few minutes before standing
up.
tell your doctor and pharmacist if you are allergic to
tramadol or other opiate pain or cough medications such as meperidine (Demerol),
morphine (Avinza, Kadian, MS Contin), codeine (in some pain medications and
cough syrups), hydrocodone (in Vicodin), hydromorphone (Dilaudid), oxycodone
(OxyContin, in Percocet), propoxyphene (Darvon, Darvon N, in Darvocet), any
other medications, or any of the ingredients in tramadol tablets or
extended-release tablets. Ask your pharmacist for a list of ingredients in
tramadol tablets or extended release tablets.
- tell your doctor and pharmacist what other prescription and
nonprescription medications, vitamins, and nutritional supplements you are
taking. Be sure to mention any of the following: antifungal medications such
as ketoconazole (Nizoral); digoxin (Lanoxin); erythromycin (E.E.S., E-Mycin,
Erythrocin); monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan),
phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), and
tranylcypromine (Parnate); medications for anxiety, mental illness, nausea,
and pain; medications for seizures, such as carbamazepine (Tegretol); muscle
relaxants such as cyclobenzaprine (Flexeril); promethazine (Phenergan);
quinidine; rifampin (Rifadin, Rifamate, Rimactane, others); sedatives;
sleeping pills; selective serotonin reuptake inhibitors (SSRIs) such as
citalopram (Celexa), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox),
paroxetine (Paxil), and sertraline (Zoloft); tranquilizers; tricylic
antidepressants such as amitriptyline (Elavil), amoxapine (Asendin),
clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan),
imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil),
and trimipramine (Surmontil);and warfarin (Coumadin). Many other medications
may also interact with tramadol, so be sure to tell your doctor about all
the medications you are taking, even those that do not appear on this list.
Your doctor may need to change the doses of your medications or monitor you
carefully for side effects.
- tell your doctor what herbal products you are taking, especially St.
John's wort.
- tell your doctor if you have or have ever had seizures; an infection in
your brain or spine; a head injury, a brain tumor, a stroke, or any other
condition that caused high pressure inside your skull; depression or
thoughts about harming or killing yourself or planning or trying to do so;
diabetes; breathing problems or lung disease; or kidney or liver disease.
Also tell your doctor if you drink or have ever drunk large amounts of
alcohol, use or have ever used street drugs, or have overused prescription
medications.
- tell your doctor if you are pregnant, plan to become pregnant, or are
breast-feeding. If you become pregnant while taking tramadol, call your
doctor.
- if you are having surgery, including dental surgery, tell the doctor or
dentist that you are taking tramadol.
- you should know that this medication may make you drowsy and may affect
your coordination. Do not drive a car or operate machinery until you know
how this medication affects you.
- talk to your doctor about the safe use of alcohol while you are taking
this medication. Alcohol can make the side effects from tramadol worse.
- you should know that tramadol may cause dizziness, lightheadedness, and
fainting when you get up from a lying position. To avoid this, get out of
bed slowly, resting your feet on the floor for a few minutes before standing
up.
What special dietary instructions should I follow?
Talk to your doctor about drinking grapefruit juice while
you are taking this medication.
What should I do if I forget a dose?
If your doctor has told you to take tramadol regularly, take
the missed dose as soon as you remember it. However, if it is almost time for
the next dose, skip the missed dose and continue your regular dosing schedule.
Do not take a double dose to make up for a missed one.
What side effects can this medication cause?
Tramadol may cause side effects. Tell your doctor if any of
these symptoms are severe or do not go away:
- dizziness
- weakness
- sleepiness
- difficulty falling asleep or staying asleep
- headache
- nervousness
- agitation
- uncontrollable shaking of a part of the body
- muscle tightness
- changes in mood
- drowsiness
- heartburn or indigestion
- nausea
- vomiting
- diarrhea
- constipation
- itching
- sweating
- chills
- dry mouth
Some side effects can be serious. If you experience any of
these symptoms or those listed in the SPECIAL PRECAUTIONS section , call your
doctor immediately:
- seizures
- sores on the inside of your mouth, nose, eyes, or throat
- flu-like symptoms
- hives
- rash
- difficulty swallowing or breathing
- swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles,
or lower legs
- hoarseness
- hallucinations (seeing things or hearing voices that do not exist)
If you experience a serious side effect, you or your doctor
may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse
Event Reporting program online [at
http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].
Tramadol may cause other side effects. Tell your doctor if
you have any unusual problems while you are taking this medication.
What storage conditions are needed for this medicine?
Keep this medication in the container it came in, tightly
closed, and out of reach of children. Store it at room temperature and away from
excess heat and moisture (not in the bathroom). Throw away any medication that
is outdated or no longer needed. Talk to your pharmacist about the proper
disposal of your medication.
In case of emergency/overdose
In case of overdose, call your local poison control center
at 1-800-222-1222. If the victim has collapsed or is not breathing, call local
emergency services at 911.
Symptoms of overdose may include:
- decreased size of the pupil (the black circle in the center of the eye)
- difficulty breathing
- extreme drowsiness
- unconsciousness
- coma
- seizure
- heart attack
What other information should I know?
Keep all appointments with your doctor.
Do not let anyone else take your medication. Ask your
pharmacist any questions you have about refilling your prescription.
Brand names
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